Postpartum Hemorrhage (PPH)

Misoprostol for postpartum hemorrhage prevention at home birth: an integrative review of global implementation experience to date

Jeffrey Michael Smith
Rehana Gubin
Martine M Holston
Judith Fullerton
Ndola Prata
2013

BACKGROUND: Hemorrhage continues to be a leading cause of maternal death in developing countries. The 2012 World Health Organization guidelines for the prevention and management of postpartum hemorrhage (PPH) recommend oral administration of misoprostol by community health workers (CHWs). However, there are several outstanding questions about distribution of misoprostol for PPH prevention at home births.

METHODS: We conducted an integrative review of published research studies and evaluation reports from programs that distributed misoprostol at the...

Confronting Maternal Mortality Due to Postpartum Hemorrhage and Unsafe Abortion: A Call for Commitment

Joseph Karanja
Projestine Muganyizi
Emmanuel Rwamushaija
Nuriye Hodoglugil
Emma Nesper Holm
Regional Experts’ Summit Group
VSI
2013

In this commentary co-authored by VSI and the Regional Experts’ Summit Group, 35 ob/gyns and public health experts from 12 countries in Africa call for political commitment to expanding access to misoprostol for its many uses in maternal health.

African Journal of Reproductive Health, 2013

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Prevention of Postpartum Hemorrhage in Five Rural Zambian Districts

VSI
UC Berkeley Bixby Center
2010

In Zambia, most of the maternal deaths due to PPH occur in places where there are few skilled birth attendants or a lack of skills or resources to manage bleeding and shock. This brief summarizes VSI’s Zambia program that trained providers on the distribution of misoprostol tablets to women in order to prevent PPH.

For the full technical report, click here.

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Prevention of Postpartum Hemorrhage in Northern Nigeria

VSI
UC Berkeley Bixby Center
2010

Postpartum hemorrhage (PPH) makes a significant contribution to the number of maternal deaths in Nigeria. This brief summarizes research demonstrating misoprostol is a safe and effective means to control PPH at home births in five communities in Northern Nigeria.

For the full technical report, click here.

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Community-based Prevention of PPH with Misoprostol in Mozambique

VSI
UC Berkeley Bixby Center
2011

This brief summarizes the final results a collaborative community-based pilot project of VSI, AMOG, the Bixby Center at UC Berkeley, and PSI. Results show that antenatal care visits and additional community-based strategies, such as TBAs, are key opportunities to reach women with misoprostol and educate them on its use for prevention of PPH.

For the full technical report, click here.

Misoprostol Distribution at Antenatal Care in Tanzania

VSI
UC Berkeley Bixby Center
2011

Final results shared at the dissemination meeting on 3 March 2011 in Dar es Salaam, Tanzania. This brief highlights results from the Ifakara Health Institute and VSI project to protect women from postpartum hemorrhage at home births in four districts of Tanzania.

For the full technical report, click here.

Scaling up of Misoprostol for Prevention of Postpartum Hemorrhage in 29 Upazilas of Bangladesh

VSI
UC Berkeley Bixby Center
2009

The results from this collaborative operations research project between the ICDDR,B, RDRS, VSI and the Bixby Center at UC Berkeley show that the incorporation of misoprostol into clean delivery kits is a feasible intervention to prevent excessive bleeding after childbirth in the high numbers of women delivering at home in this densely populated country.

For the full technical report, click here.

Introduction of Misoprostol for Prevention of Postpartum Hemorrhage in Two Kenyan Districts

VSI
2011

This brief summarizes the findings of the VSI/KOGS misoprostol for PPH pilot program in Kenya, including that the direct distribution of misoprostol to women through antenatal care visits, as well as through Community Midwives at delivery, increased the number of women who receive protection from postpartum hemorrhage.

Click here for the full technical report.

Distribution of Misoprostol at Antenatal Care Visits for the Prevention of Postpartum Hemorrhage in Ghana

VSI
2012

This brief summarizes the final results from a collaborative project of the VSI/Ghana Health Service pilot program in Ghana to address maternal deaths due to postpartum hemorrhage. The results demonstrate that the distribution of misoprostol through antenatal care visits increased the number of women who received protection from postpartum hemorrhage and is a key opportunity to reach more mothers with safe motherhood messages and ultimately reduce maternal deaths.

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New global guidance supports community and lay health workers in postpartum hemorrhage prevention

VSI
2013

VSI CEO, Pam Norick; Family Care International President, Ann Starrs; and Drs. Clara Ejembi (Ahmadu Bello University, Nigeria) and Kasum Thapa (Jhpiego-Asia Region), published a commentary highlighting new global recommendations and case examples from Nigeria and Nepal that illustrate community engagement and empowerment as critical strategies in successful postpartum hemorrhage (PPH) programming with misoprostol.

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