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Publications: viewing all articles about Misoprostol

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Commentary, Journal

Maternal mortality: one death every 7 min

Potts M, Prata N, Sahin-Hodoglugil N

Lancet, 2010

This comment in the Lancet explores the role of policy and research in using the prevention of postpartum hemorrhage and suggest a joint meeting by WHO and FIGO to revisit the 2009 statement by WHO which does not recommend the use of misoprostol at the community level.

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Commentary

Criticism of misguided Chu et al. article

Potts M, Gerdts C, Prata N, Okonofua F, Sahin-Hodoglugil N, Hosang N, Weidert K, Fraser A, Bell S

Journal of the Royal Society of Medicine, 2012

Chu, Brhlikova and Pollock's article suggests the WHO rethink its decision to include misoprostol on the Essential Medi- cines List. Their paper is a sad example of workers in an elite setting advocating policies with the potential to endanger the lives of thousands of vulnerable women in low-resource settings.

Published in Journal of the [...]

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Journal

Maternal mortality in developing countries: challenges in scaling-up priority interventions

Prata N, Passano P, Sreenivas A, Gerdts C

Women's Health, 2010

A review of the interventions targeted at maternal mortality reduction demonstrates that most developing countries face tremendous challenges in the implementation of these interventions, including the availability of unreliable data and the shortage in human and financial resources, as well as limited political commitment.

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Journal

Setting priorities for safe motherhood interventions in resource-scarce settings

Prata N, Sreenivas A, Greig F, Walsh J, Potts M

Health Policy, 2010

Objective: Guide policy-makers in prioritizing safe motherhood interventions.

Methods: Three models (LOW, MED, HIGH) were constructed based on 34 sub-Saharan African countries to assess the relative cost-effectiveness of available safe motherhood interventions. Cost and effectiveness data were compiled and inserted into the WHO Mother Baby Package Costing Spreadsheet. For each model we assessed the [...]

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Journal

Where There Are (Few) Skilled Birth Attendants

Prata N, Passano P, Rowen T, Bell S, Walsh J, Potts M

Journal of Health, Population, and Nutrition, 2011

Recent efforts to reduce maternal mortality in developing countries have focused primarily on two long-term aims: training and deploying skilled birth attendants and upgrading emergency obstetric care facilities. Given the future population-level benefits, strengthening of health systems makes excellent strategic sense but it does not address the immediate safe-delivery needs of the estimated 45 million [...]

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Journal

Training traditional birth attendants to use misoprostol and an absorbent delivery mat in home births

Prata N, Quaiyum M, Passano P, Bell S, Bohl D, Hossain S, Azmi A, Begum M

Social Science & Medicine, 2012

A 50-fold disparity in maternal mortality exists between high- and low-income countries, and in most contexts, the single most common cause of maternal death is postpartum hemorrhage (PPH). In Bangladesh, as in many other low-income countries, the majority of deliveries are conducted at home by traditional birth attendants (TBAs) or family members. In the absence [...]

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Journal

New hope: community-based misoprostol use to prevent postpartum haemorrhage

Prata N, Passano P, Bell S, Rowen T, Potts M

Health Policy and Planning, 2013

The wide gap in maternal mortality ratios worldwide indicates major inequities in the levels of risk women face during pregnancy. Two priority strategies have emerged among safe motherhood advocates: increasing the quality of emergency obstetric care facilities and deploying skilled birth attendants. The training of traditional birth attendants, a strategy employed in the 1970s and [...]

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Journal

Prevention of postpartum hemorrhage in low-resource settings: current perspectives

Prata N, Bell S, Weidert K

International Journal of Women's Health, 2013

BACKGROUND: Postpartum hemorrhage (PPH) is the leading cause of maternal death in low-income countries and is the primary cause of approximately one-quarter of global maternal deaths. The purpose of this paper is to provide a review of PPH prevention interventions, with a particular focus on misoprostol, and the challenges and opportunities that preventing PPH in [...]

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Journal

Prevention of postpartum hemorrhage at home birth in Afghanistan

Sanghvi H, Ansari N, Prata N, Gibson H, Ehsan A, Smith J

International Journal of Gynecology and Obstetrics, 2010

The Objective of this research is to safety, acceptability, feasibility, and effectiveness of community-based education and distribution of misoprostol for prevention of postpartum hemorrhage at home birth in Afghanistan.

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Misoprostol for postpartum hemorrhage prevention at home birth: an integrative review of global implementation experience to date

Smith J, Gubin R, Holston M, Fullerton J, Prata N

BMC Pregnancy and Childbirth, 2013

BACKGROUND: Hemorrhage continues to be a leading cause of maternal death in developing countries. The 2012 World Health Organization guidelines for the prevention and management of postpartum hemorrhage (PPH) recommend oral administration of misoprostol by community health workers (CHWs). However, there are several outstanding questions about distribution of misoprostol for PPH prevention at home births.
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